Mannitol is a hexahexanol. Due to its heat absorption during dissolution and sweet taste, it provides a comfortable sensation in the mouth. Therefore, it is more widely used in the production of sobering pills, mouth coolants and other chewable tablets. Its granular form is specifically used as an excipient for direct tablet pressing. Mannitol can be used as the base material for nitroglycerin tablets.
CAS No. :
87-78-5EINECS :
201-770-2Package :
25KG/BAGBrand :
TOPINCHEM®Origin :
CHINAFormula :
C6H14O6Minimum Order :
200KGItem :
MannitolDescription
Mannitol, also known as mannitol, is a six-carbon polyol extracted from brown algae cells and has two configurations: D and L. The L-configuration is a synthetic product and does not exist in nature. The D configuration is widely distributed in the plant kingdom. Especially, the content of mannitol is very high in Marine brown algae of the Kelp family. Mannitol is a storage substance in the cells of brown algae, and large brown algae such as kelp are the main raw materials for extracting mannitol. Mannitol extracted from kelp, when combined with niacin to form niacin mannitol ester, has a significant effect in alleviating angina pectoris and has a good therapeutic effect on hyperlipidemia. It can treat conditions such as high cholesterol, high blood pressure and arteriosclerosis.
Specification
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ITEM
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STANDARD
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||
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Appearance
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White crystalline powder
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White crystalline powder
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Conformity
|
|
Identification C: Infrared absorption spectrophotometry
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Conformity
|
Conformity
|
Conformity
|
|
Identification A: Specific optical rotation
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+23°~ +25°
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+24.0
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Conformity
|
|
Identification B: Melting point
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165°C~170°C
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166-168°C
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Conformity
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|
Identification D: TLC
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Conformity
|
Conformity
|
Conformity
|
|
Appearance of solution
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Clear and colourless
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Clear and colourless
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Conformity
|
|
Solubility
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Freely soluble in water,
practically insoluble in
ethanol
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Conformity
|
Conformity
|
|
Conductivity
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≤20us/cm
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2.1us/cm
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Conformity
|
|
Reducing sugars
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≤0.1%
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<0.1%
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Conformity
|
|
Related substances:
Sorbitol
Maltitol and Isomalt
Unspecified impurities
Total impurities
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≤2.0%
≤2.0%
≤0.10%
≤2.0%
|
0.2%
Not detected
Not detected
0.2%
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Conformity
|
|
Heavy metals
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≤5 ppm
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<5ppm
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Conformity
|
|
Nickel
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≤1 ppm
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<1 ppm
|
Conformity
|
|
Loss on drying
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≤0.5%
|
0.1%
|
Conformity
|
|
Microbial contamination:
TAMC
TYMC
Escherichia coli
Salmonella
Staphylococcus Aureus
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≤100 CFU/g
≤100 CFU/g
Negative
Negative
Negative
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<10 CFU/g
<10 CFU/g
Negative
Negative
Negative
|
Conformity
|
|
Bacterial endotoxins
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<2.5 IU/g
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<2.5IU/g
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Conformity
|
|
Assay
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98.0% ~ 102.0%
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99.8%
|
Conformity
|
|
Conclusion
|
Conformity
|
Conformity
|
Conformity
|
Application
1. Food mannitol is one of the commonly used sugar alcohol and sugar substitutes, commonly used as an ingredient in sugar free chewing gum.
2. Medicine is used as a large infusion solution for injection, which is used to reduce brain pressure, intraocular pressure, and eliminate brain edema; Used as a diuretic; Renal function and intestinal examination; Due to edema and burns causing oliguria and renal failure, mannitol infusion has a certain therapeutic effect; Compound infusion with amino acids.
3. Chemical mannitol is esterified and etherified to produce various resins and surfactants.