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Wholesale Antibiotic Polymyxin B Sulfate CAS 1405-20-5

Wholesale Antibiotic Polymyxin B Sulfate CAS 1405-20-5

  • CAS No. :

    1405-20-5
  • EINECS :

    215-774-7
  • Package :

    2KG/TIN
  • Brand :

    TOPINCHEM®
  • Origin :

    CHINA
  • Formula :

    C56H100N16O17S
  • Minimum Order :

    2KG
  • Item :

    Polymyxin B Sulfate

 

Description

Polymyxin B (polymyxin b sulfate) is an antibiotic used to treat bacterial infections such as urinary tract infections, meningitis, blood infections, and eye infections. Polymyxin B is available in generic form.

 

Specification 

Tests Specifications Results
Description White or almost white powder,hygroscopic Conforms
Identification HPLC identification test,Conforms

Conforms

 

Areddish violet color is produced,Conforms
Meets the requirements of the test for Sulfate ,Conforms
PH(0.5%) 5.07.5 5.9
Loss on drying ≤7.0% 4.20%

Res

 

idue on ignition

≤5.0% 0.25%
Any impurity:≤3.0% 2.10%
Related substances,HPLC Sum of impurity:≤17.0% 7.20%
Total viable aerobic count ≤100CFU/g Conform
Potency(Dried basis) ≥6000IU/mg 8135IU/mg
Assay HPLC (Dried basis) Sum of polymyxin B1,B2,B3 and B1-I:≥80.0% 96.10%
Polymyxin B3:≤6.0% 1.30%
Polymyxin B1-I:≤15.0% 14.30%
Particle size
(Neither USP nor EP has this)
99.0%:Not more than 30μm by vol. Conforms
90.0%:Not more than 20μm by vol
75.0%:Not more than 15μm by vol
35.0%:Not more than 5μm by vol
Mean diameter:Not more than 10μm

 

 

Application

Antibiotic Polymyxin B  Sulfate used for the treatment of serious gram-negative infections, including those caused by Pseudomonas. However, aminoglycosides and extended spectrum penicillins are generally the drugs of choice for these conditions.

 

 

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