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Tylosin Phosphate Powder CAS 1405-53-4 antibiotic

Tylosin Phosphate Powder CAS 1405-53-4 antibiotic

Tylosin phosphate powder is a veterinary-specific macrolide antibiotic that features ​potent anti mycoplasma activity, broad spectrum antibacterial efficacy, and low residue characteristics, specifically designed for the high-efficacy treatment of respiratory and complex infections in livestock and poultry.

  • CAS No. :

    1405-53-4
  • EINECS :

    215-779-4
  • Package :

    15kg/Carton
  • Brand :

    Topinchem
  • Formula :

    C46H80NO21P

Description
Tylosin phosphate is the phosphate salt form of tylosin, a macrolide antibiotic specifically for animal use. Tylosin was first isolated from the culture broth of Streptomyces fradiae (an actinomycete genus) in the United States in 1959. In vivo, tylosin exists in the form of tylosinol, where it exerts bacteriostatic and bactericidal effects by binding to the ribosomes of pathogenic microorganisms, inhibiting the activity of translocase, blocking mRNA translocation, and hindering peptide chain elongation. This mechanism disrupts protein synthesis in sensitive microorganisms.
Specification

Test Items

 

Specifications

Test Results

Items

Conclusion

Description

White to pale yellow powder

Pale yellow powder

Complies

 

Solubility

Freely soluble in Chloroform;Soluble in Water or Methanol;Insoluble in Ether.

 

Complies

 

Complies

Identification

Positive

Positive

Complies

Chromatogram

Complies

Complies

 

pH

 

5.0-7.5

 

6.1

Complies

Loss on Drying

≤5.0%

 

2.1%

Complies

Residue on Ignition

≤5.0%

 

0.55%

Complies

Heavy Metals

≤20ppm

<20ppm

Complies

Tyramine

 

Absorption of sample solution is not more than the control solution

Complies

Complies

Potency

≥800u/mg

889.2u/mg(Wet) 908u/mg(Dry)

Complies

Tylosin Compositions

Tylosin A≥80% A+B+C+D≥95%

90.46%

97.32%

Complies

Application

  1. ​Anti-mycoplasma Activity: Exhibits strong inhibitory effects against Mycoplasma hyopneumoniae (Contagious bovine pleuropneumonia) and other mycoplasmas, making it the ​drug of choice for mycoplasmosis in livestock and poultry.
  2. ​Broad-Spectrum Antimicrobial Activity: Primarily targets ​Gram-positive bacteria (e.g., Streptococcus, Staphylococcus). Also effective against some ​Gram-negative bacteria, campylobacters, spirochetes, and demonstrates ​anticoccidial effects.
  3. ​Rapid Absorption and Excretion: Achieves therapeutic concentrations within ​minutes (oral or injectable) and maintains efficacy for extended periods. Rapidly eliminated post-treatment, with ​minimal residual accumulation in tissues.
  4. ​Excellent Tissue Penetration: Diffuses into all organs, tissues, and body fluids, including serous membranes, blood-brain, blood-ocular, and blood-testicular barriers, enabling ​broad clinical applications.
  5. ​Species-Specific Application: Exclusively used in veterinary medicine, avoiding ​cross-resistance issues associated with human-animal shared antibiotics.

Packaging
15kg/Carton

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