Aspirin (acetylsalicylic acid) is a white crystalline or crystalline powder, odorless or with odor of acetic acid, slightly soluble in water, soluble in ethanol, soluble in ether, chloroform, and acidic in aqueous solution.
CAS No. :
50-78-2EINECS :
200-064-1Package :
25KG/DRUMBrand :
TOPINCHEM®Origin :
CHINAFormula :
C9H8O4Minimum Order :
200KGItem :
Acetylsalicylic AcidTop Grade High Purity Acetylsalicylic Acid CAS 50-78-2
Description
Aspirin has been found to inhibit platelet aggregation and prevent thrombus formation. It is clinically used to prevent the formation of thrombus after transient ischemic attack, myocardial infarction, artificial heart valve and venous fistula or other surgeries.
Specification
| Items | Standard | Results |
| Appearance | White or almost white, crystalline powder or colorless crystals | White crystalline powder |
| Identification (BP2009) | ||
| A.IR-Spectrum | Complies | Complies |
| B.Melting point of salicylic acid(°C) | 156-161 | 158 |
| Identification (USP32) | ||
| A.Ferric Acid reaction test | Complies | Complies |
| B.IR-Spectrum | Complies | Complies |
| Appearance of solution | Clear and colorless | Clear and colorless |
| Readily carbonizable substances | ≤Fluid Q | ≤Fluid Q |
| Substances Insoluble in Sodium | Clear | Clear |
| Chloride (%) | ≤0.014 | <0.014 |
| Sulfate (%) | ≤0.04 | <0.04 |
| Limit of free salicylic acid (%) | ≤0.1 | <0.1 |
| Heavy metals | ≤10PPM | <10PPM |
| Loss on Drying | ≤0.5 | 0.2 |
| Sulphated ash (Residue on ignition (%) | ≤0.05 | 0.03 |
| Related Substances/Any single impurity (%) | ≤0.1 | 0.07 |
| Related Substances/Total impurities (%) | ≤0.25 | 0.07 |
| Assay (%) | 99.5-100.5 | 100.1 |
| Residual Solvents (%) | USP (467) | Complies |
Application
1. Pain In general
Aspirin works well for dull, throbbing pain; it is ineffective for pain caused by most muscle cramps, bloating, gastric distension, and acute skin irritation
2. Headache
Aspirin is a first-line drug in the treatment of migraine, bringing relief in 50-60% of the cases.
3. Prevention of heart attacks and stroke
There are two distinct uses of Aspirin for prophylaxis of cardiovascular events: primary prevention and secondary prevention. Primary prevention is about decreasing strokes and heart attacks in the general population of those who have no diagnosed heart or vascular problems. Secondary prevention concerns patients with known cardiovascular disease.
4. Coronary and carotid arteries, bypasses and stents
The coronary arteries supply blood to the heart. Aspirin is recommended for one to six months after placement of stents in the coronary arteries and for years after a coronary artery bypass graft.
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