Chlortetracycline Hydrochloride CAS 57-62-5 is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity.
CAS No. :
57-62-5EINECS :
200-341-7Package :
25KG/DRUMBrand :
TOPINCHEM®Origin :
CHINAFormula :
C22H23ClN2O8Minimum Order :
500KGItem :
Chlortetracycline HydrochlorideTop Quality Chlortetracycline Hydrochloride CAS 57-62-5
Description:
Chlortetracycline Hydrochloride CAS 57-62-5 is a specific and potent calcium ionophore antibiotic. The compound has been shown to inhibit binding of aminoacyl-tRNA to ribosomes. In endoplasmic reticulum studies Chortetracycline has been used as a fluorescent dye to analyze calcium changes during apotosis, and in other processes. Chlortetracycline has been shown to block platelet secretion and can affect 17β-estradiol (E2) synthesis in H295R cells. Kupffer cell studies have shown that Chlortetracycline can inhibit secretion of TNF α. We offer the Chlortetracycline Hydrochloride form.
Specification:
| NO. | TESTS | SPECIFICATIONS | RESULTS |
| 1 | Appearance | Yellow powder | Conforms |
| 2 | Identification | ||
| 2.1 | A(Current Ph.Eur.2.2.27) | Thin-Layer Chromatography | Positive |
| 2.2 | B(Current Ph.Eur.0173) | The colour becomes brownish | Positive |
| 2.3 | C(Current Ph.Eur.2.3.1) | It gives reaction (a) of chlorides | Positive |
| 2.4 | D(Current Ph.Eur.2.2.29) | Liquid chromatography | Positive |
| 3 | pH(Current Ph.Eur.2.2.3) | 2.3~3.3 | 2.6 |
| 4 | SpecificOpticalRotation(CurrentPh.Eur.2.2.7) | -250°~-235(anhydrous substance) | -245° |
| 5 | Absorbance(Current Ph.Eur.2.2.25) | ≤0.40,460nm | 0.28 |
| 6 | Related substances(Current Ph.Eur.2.2.29) | ||
| 6.1 | Impurity A (4-epichlortetracycline) | ≤4.0% | 1.56% |
| 6.2 | Impurity B(demeclocycline) | ≤1.0% | 0.07% |
| 6.3 | Impurity E(4-epidemethylchlortetracycline) | ≤1.0% | 0.70% |
| 6.4 | Impurity J(anhydrotetracycline) | ≤0.3% | 0.09% |
| 6.5 | Impurity D(4-epitetracycline) | ≤0.2% | 0.08% |
Application:
A combination cream with triamcinolone acetonide is available for the treatment of infected allergic dermatitis in humans.
In veterinary medicine, feed additive chlortetracycline hydrochloride is commonly used to treat conjunctivitis in cats, dogs and horses. It is also used to treat infected wounds in cattle, sheep and pigs, and respiratory tract infections in calves, pigs and chickens.
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