Azithromycin is a widely used antibiotic drug in clinical practice.
CAS No. :
83905-01-5EINECS :
617-500-5Package :
25KG/DRUMBrand :
TOPINCHEM®Origin :
CHINAFormula :
C38H72N2O12Minimum Order :
200KGItem :
AzithromycinActive Pharmaceutical Ingredients Azithromycin CAS 83905-01-5
Description
Azithromycin is currently the most widely used macrolide antibacterial drug in clinical practice. It has strong antibacterial effects, long antibacterial time, wide antibacterial spectrum, low resistance rate, stable gastric acid, high oral bioavailability, wide tissue distribution, good permeability, long tissue half-life, good adherence, and few adverse reactions.
Specification
| Optical rotation | -45° ~-49° | -47° |
| Crystallinity | Meets the requirement. | Meets the requirement. |
| PH | 9.0~11.0 | 10.2 |
| Water | 4.0~5.0% | 4.5% |
| Related substances (Procedure 2) (HPLC) -AzithromycinN-oxide |
≤0.5% | N.D. |
| -3'-(N,N-Didemethyl)-3'-N-formyl-azithromycin | ≤0.5% | N.D. |
| -3'-(N,N-A9Didemethyl) azithromycin (aminoazithromycin) |
≤0.5% | N.D. |
| -Azithromycin related compound F | ≤0.5% | N.D. |
| -Desosaminylazithromycin | ≤0.3% | N.D. |
| -3'-M{[4-(Acetylamino)phenyl]sulfonyI}-3',3'- didemethylazithromycin |
≤0.15% | N.D. |
| -N-Demethylazithromycin | ≤0.5% | N.D. |
| -Azithromycin C (3"-O-demethylazithromycin) | ≤0.5% | N.D. |
| -3'-De(dimethylamino)-3'-oxoazithromycin | ≤0.5% | N.D. |
| -3'-N-{[4-(Acetylamino)phenyl]sulfonyl}-3'- demethylazithromycin |
≤0.5% | N.D. |
| -Azaerythromycin A | ≤0.5% | N.D. |
| -Azithromycin impurity P | ≤0.2% | N.D. |
| -2-Desethyl-2-propyl-azithromycin | ≤0.5% | 0.1% |
| -3'-N-Demethyl-3'-N-[(4-methylphenyl) sulfonyllazithromycin |
≤0.2% | N.D. |
| -3-Deoxyazithromycin(azithromycin B) | ≤0.5% | 0.2% |
| '-Erythromycin Aiminoether | ≤1.0% | N.D. |
Application
Azithromycin is used for respiratory infections, urinary tract infections, skin and soft tissue infections, and sexually transmitted diseases.
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